Pharmaceutical Capsules

Product Details:

• Each hard gelatin capsule contains.
• Enzalutamide 40 mg.
• excipients .q.s.
• Approved colours used in capsule shell.

Product Details:

Posaconazole is an antifungal medication available in tablet form, and it is used to prevent and treat various fungal infections. Here is a detailed overview of posaconazole tablets:

1. Prophylaxis:

   • Prevents invasive Aspergillus and Candida infections in immunocompromised patients, such as those undergoing chemotherapy for hematologic malignancies or hematopoietic stem cell transplant (HSCT) recipients.

2. Treatment:

   • Oropharyngeal candidiasis, especially in cases refractory to other treatments.
   • Other fungal infections, including zygomycosis, fusariosis, and chromoblastomycosis, particularly in patients who are intolerant to or have infections resistant to other antifungal agents.

Posaconazole is a triazole antifungal that works by inhibiting the enzyme lanosterol 14-alpha-demethylase, crucial for converting lanosterol to ergosterol. Ergosterol is an essential component of the fungal cell membrane. By inhibiting its synthesis, posaconazole disrupts the cell membrane, leading to fungal cell death.

• Dosage: The dosage and duration of posaconazole treatment depend on the type and severity of the infection.
  • For prophylaxis, the typical dose is 300 mg twice a day on the first day, followed by 300 mg once daily.
  • For oropharyngeal candidiasis, the usual dose is 100 mg twice daily on the first day, followed by 100 mg once daily for 13 days.
• Instructions: Posaconazole tablets should be taken with food to enhance absorption. It's crucial to follow the prescribed schedule without missing doses.

• Common:

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Abdominal pain

• Serious:

  • Hepatotoxicity (liver toxicity)
  • QT prolongation (a type of heart rhythm disorder)
  • Severe allergic reactions
  • Electrolyte imbalances (low potassium, magnesium, etc.)

Patients on posaconazole should be monitored for:

• Liver function tests (LFTs)
• Electrolyte levels (potassium, magnesium)
• Signs and symptoms of heart rhythm disorders

• Drug Interactions: Posaconazole can interact with several medications, including certain statins, ergot alkaloids, and other drugs metabolized by the CYP3A4 enzyme. It is important to inform healthcare providers of all medications being taken.
• Renal and Hepatic Impairment: Dose adjustments may be required in patients with renal or hepatic impairment.
• Pregnancy and Breastfeeding: The safety of posaconazole in pregnant or breastfeeding women has not been established, so it should be used only if the potential benefits justify the potential risks.

Product Details:

• Each soft gelatin capsule contains:
• Enzalutamide 40 mg. 
• Excipients q.s.
• approved colours used in capsule shell.
• store below 30"C.

Product Details:

• Each hard gelatin capsule contains:
• Ibrutinib 140 mg.
• Excipients qs.
• Approved colours used by the oncoiogist.
• Store below 30"C.